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为解决肝癌多支供血及肝动脉栓塞后的侧支开通问题，消灭栓塞盲区，寻求一种较为理想的终末动脉栓塞剂治疗晚期肝癌。本课题将自体毛发粉碎灭菌后混入抗癌药及造影剂，经导管超选择灌入靶动脉，进行８只动物实验并治疗８例晚期肝癌。在灌注前后作ＣＴ、Ｂ超、ＤＳＡ及ＡＦＰ等对照检测。结果证明体毛药液可顺利通过导管随血液流入口径为１００～２００μｍ的末梢小动脉中停留，无异位栓塞和排异反应。体毛在永久性栓塞的同时将抗癌药限制在肿瘤局部缓慢释放。栓塞后副反应小，临床疗效满意
In order to solve the problems of multiple branches of hepatocellular carcinoma and side branch opening after hepatic artery embolization, the blind area of embolism was eliminated and a more ideal endarterial embolization agent was used to treat advanced hepatocellular carcinoma. In this study, autogenous hair was sterilized and mixed with anti-cancer drugs and contrast agents. The catheters were superselectively injected into the target artery. Eight animals were tested and eight cases of advanced liver cancer were treated. CT, B-ultrasound, DSA and AFP were detected before and after perfusion. The results showed that the body hair liquid can smoothly pass through the catheter with the blood flow inlet diameter of 100 ~ 200μm in the distal arterioles to stay, no ectopic embolization and rejection. Body hair, while permanently embolized, limits the anticancer drug to slow release locally on the tumor. Small side effects after embolization, satisfactory clinical results