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目的研究留置胃管反复洗胃联合重复血液灌流(HP)治疗急性重度有机磷农药中毒(ASOPP)的效果。方法对照组(n=68)采用一次性洗胃,一次 HP 联合常规内科治疗;治疗组(n=22)采用留置胃管反复洗胃,重复 HP 联合常规内科治疗。结果治疗组和对照组比较,患者昏迷时间、机械通气时间、住院时间均显著缩短(P<0.01),治愈率显著提高(P<0.01)结论留置胃管反复洗胃联合重复 HP 可提高 ASOPP 的抢救成功率。
Objective To study the effect of gastric lavage with repeated gastric lavage combined with repeated hemoperfusion (HP) on acute severe organophosphorus pesticide poisoning (ASOPP). Methods The control group (n = 68) received one-time gastric lavage and once HP combined with conventional medical treatment. The treatment group (n = 22) was treated with repeated gastric lavage with gastric lavage and repeated HP combined with conventional medical treatment. Results Compared with the control group, the coma time, mechanical ventilation time and hospitalization time in the treatment group were significantly shorter (P <0.01), and the cure rate was significantly increased (P <0.01). Conclusions Indirect gastric lavage with repeated gastric lavage combined with repeated HP can increase ASOPP Rescue success rate.