乳腺癌是欧美妇女最常见的恶性肿瘤,发病率为8%～9% ,且持续增长。我国上海2 0 0 0年乳癌发病率为5 6 .2 /10万。受治患者中大约5 0 %发生转移性病变,大多只能进行化疗。但目前在紫杉类和蒽环类治疗失败后,尚没有标准的替代方案,我们于2 0 0 1年1月至2 0 0 3年6月对17例晚期乳 Breast cancer is the most common malignant tumor in Europe and the United States, the incidence rate of 8% to 9%, and continued to grow. The incidence of breast cancer in Shanghai in China was 56.2 / 100,000 in 2000. Approximately 50% of the treated patients develop metastatic disease, and most often only chemotherapy. However, at present, there is no standard alternative to the treatment of taxanes and anthracyclines. From January 2001 to June 2003, 17 cases of late milk