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目的评价冻干水痘减毒活疫苗(Varicella Freeze-dried Attenuated Live Vaccine,VarV)的现场流行病学效果和疫苗安全性。方法选择未发生过水痘流行、无水痘患病史、未接种过VarV的小学生和托幼机构儿童作为观察对象,采取随机、盲法、对照的方法 ,将入选的观察对象分成试验组2588人,接种VarV;对照组2598人,接种流行性腮腺炎减毒活疫苗。结果经追踪随访,试验组发病率为2.70‰,对照组为14.63‰。结论具有良好的现场流行病学保护效果和安全性。
Objective To evaluate the field epidemiology and vaccine safety of Varicella Freeze-dried Attenuated Live Vaccine (VarV). Methods The subjects who had never had any chickenpox epidemic, no history of chickenpox, no pups and kindergarten children who had not been vaccinated with VarV were selected as observation subjects. The randomized, blinded and controlled methods were adopted to divide the selected subjects into experimental groups of 2588, Inoculation VarV; control group of 2598 people, vaccination of mumps live attenuated vaccine. The results were followed up, the incidence of the experimental group was 2.70 ‰, the control group was 14.63 ‰. Conclusion has good field epidemiological protection and safety.