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凡是影响前列腺素生物合成的药品概可引起敏感者气喘,荨麻疹或鼻溢液,单独或合并发生。最常见的药品是乙酰水杨酸(阿司匹林),但其他止痛刺和某些食物的着色剂及防腐剂也可有此危害。在文献中因使用这些物质而仅有声嘶症状的病例尚无报道。本文提出两例报告。一例为41岁男性,因近3、4年来经常感冒,感冒时说话声音嘶哑甚至失声。到变态反应科检查。自述无过敏史,但曾于服阿司匹林后有发痒感。予服酒石黄(tartrazine)作激发试验(0,0.1,1.0和10mg,每剂隔20分钟),服完最高量后即发生
Anything that affects prostaglandin biosynthesis can cause asthma, urticaria or rhinorrhea in sensitive individuals, either alone or in combination. The most common drug is acetylsalicylic acid (aspirin), but other painkillers and some food coloring and preservatives can also be harmful. No cases of hoarseness-related symptoms have been reported in the literature due to the use of these substances. This article presents two reports. An example is a 41-year-old man who has had a common cold in the past 3-4 years, a hoarse voice or even a speechless voice. To the allergy examination. Readme no history of allergies, but once had itch after serving aspirin. Tartrazine was given as an excitation test (0, 0.1, 1.0, and 10 mg, every 20 minutes) and occurred after the highest dose