细胞在癌变过程中,由于基因结构改变或基因表现异常,和由于适应环境变化发生了代谢变异。从而导致酶的合成和活性的改变。研究癌前细胞和癌细胞的酶活性变化,对于肿瘤的早期诊断,监视病情的发展或缓解以及予示治疗效果等方面均有着重要意义。癌变时细胞膜的结构和通透性也发生了改变,因而在肿瘤细胞中可溶性酶的合成增强或减弱,往往反应到血清,其他体液或尿中酶活性的变动,其中有些酶的变化及其反应产物,甚至在癌变的早 In the process of carcinogenesis, cells undergo metabolic changes due to changes in gene structure or gene expression, and due to adaptation to environmental changes. This leads to changes in enzyme synthesis and activity. The study of changes in the enzymatic activity of pre-cancerous and cancerous cells is of great significance in the early diagnosis of tumors, in the monitoring of the development or remission of the disease, and in the presentation of therapeutic effects. The structure and permeability of the cell membrane also change during cancerous transformation, so that the synthesis of soluble enzymes in the tumor cells is enhanced or weakened, and often reacts to changes in serum, other body fluids or urinary enzymatic activity, and some of the enzyme changes and their reactions Product, even early in cancer