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目的通过对2013年-2014年沈阳市流感监测结果进行分析,了解流感流行规律,为制定流感防控措施提供依据。方法采集全市哨点医院和暴发疫情的流感样病例数据和样本,对病原学的监测结果资料进行整理分析。结果2013年-2014年沈阳市流感样病例占就诊病例的4.75%。全市哨点医院共采集流感样病例咽拭标本1 321份,流感病毒核酸检测阳性率为20.06%,分离到135株流感病毒,分离率为50.94%。其中甲型H1N1型71株(52.59%)、B型(Yamagata系)51株(37.78%)、季节性流感H3N2型13株(9.62%)。全市报告流感疫情2起,均为B型流感暴发,其中1起为B型混合感染。结论 2013年-2014年沈阳市流感活动高峰后移,核酸检测结果更能准确地反映流感流行情况,流感毒株对MDCK细胞系敏感度下降。
Objective To analyze the influenza epidemic in Shenyang from 2013 to 2014 to understand the prevalence of influenza and provide evidence for the development of influenza prevention and control measures. Methods The data and samples of influenza-like cases from the sentinel hospitals and the outbreak in the city were collected, and the results of the etiological monitoring were analyzed. Results In 2013-2014, 4.75% of the cases were flu-like in Shenyang City. A total of 1 321 swab samples of influenza-like cases were collected from the sentinel hospitals in the city. The positive rate of influenza virus nucleic acid detection was 20.06%. A total of 135 influenza viruses were isolated with a separation rate of 50.94%. Among them, 71 strains (52.59%) of type A H1N1, 51 strains (37.78%) of type B (Yamagata) and 13 strains (9.62%) of seasonal influenza H3N2. The city reported 2 flu outbreaks, all of which were type B influenza outbreaks, of which 1 was a B-type mixed infection. Conclusion From 2013 to 2014, the peak of influenza activity in Shenyang was postponed. The result of nucleic acid detection could reflect the prevalence of influenza more accurately. The sensitivity of influenza virus to MDCK cell line decreased.