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降粘胶囊是防治高血粘滞综合征、冠心病及缺血性脑血管病的纯中药制剂。本项研究证明降粘胶囊:①能使高脂模型大鼠血汗的TC、(LDL+VLDL)-C、AI及TC/HDL-C明显下降,P<0.01。②对高脂模型大鼠的血小板聚集率有明显的抑制作用,强于茶色素(大剂量),P<0.05。③对小鼠耳廓微循环障碍有明显的改善作用,亦强于茶色素。本研究结果为探讨降粘胶囊的疗效原理以及该药的临床广泛应用提供了动物实验依据。
Viscosity reducing capsule is a pure Chinese medicine preparation for preventing and treating hyperviscosity syndrome, coronary heart disease and ischemic cerebrovascular disease. This study shows that Jiangzao Capsule: ① can make hyperlipidemic model of rats sweat TC, (LDL + VLDL) -C, AI and TC / HDL-C decreased significantly, P <0.01. ② The platelet aggregation rate of high-fat model rats significantly inhibited, stronger than the tea pigment (high dose), P <0.05. ③ auricular microcirculation in mice significantly improved the role, but also stronger than the tea pigment. The results of this study provide an experimental basis for exploring the curative effect of the viscosity-reducing capsule and its clinical application.