作者调查32例克隆病,发现其中30例伴有齿龈及口腔粘膜损害,作者研究此30例的病史、临床经过,并对口腔粘膜损害处进行了组织学研究。在发现胃肠道损害前1.5～2年出现齿龈出血和瘙痒者25例,其中8例并有口腔粘膜溃疡形成,应用防腐剂及抗生素治疗齿龈炎和口腔炎疗效较差。推测这些克隆病患者的口腔损害是初发,以后病变向胃肠 The authors investigated 32 cases of Crohn’s disease and found 30 of them with gingival and oral mucosal damage. The authors studied the history of the 30 cases, clinically passed, and carried out histological studies on oral mucosal lesions. 25 cases of gingival bleeding and pruritus occurred in 1.5 to 2 years before gastrointestinal damage was found, of which 8 cases had oral mucosal ulcer formation. The use of preservatives and antibiotics to treat gingivitis and stomatitis was less effective. Presumably these patients with oral disease is the initial onset of colon disease, later lesions to the gastrointestinal