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调查伤寒流行地区两地居民4023人,一年内伤寒发病186例,发病率462.3/万。检出带菌者21例,带菌率0.5%。对发病较多的甲地759户居民中165例伤寒病人进行家庭聚集性分析,提示伤寒病例分布有明显的家庭聚集性、伤寒在家庭内传播起重要作用。对有关流行因素分析亦表明,有家庭内伤寒接触史((?)R=2.1),以及家庭内伤寒带菌者的存在(OR=6.3)是促使伤寒发病增多的重要因素。因此建议在伤寒流行地区的防治工作中,应重视家庭内传染源的监测、管理和易感人群的防护。
In the area of typhoid epidemic, there were 4023 residents surveyed and 186 cases of typhoid fever in one year, with a prevalence of 462.3 / million. Twenty-one carriers were detected, with a carrier rate of 0.5%. A total of 165 cases of typhoid fever among 759 residents in A district were analyzed retrospectively. The results showed that there was obvious familial aggregation in typhoid cases, and typhoid fever played an important role in family transmission. An analysis of the prevalence factors also showed that there was a history of exposure to typhus (R = 2.1) in families and the presence of domestic pathogens (OR = 6.3) as an important factor contributing to the increased incidence of typhoid fever. Therefore, it is suggested that in the prevention and treatment of typhoid fever endemic areas, attention should be paid to the monitoring and management of sources of infection within the family and the protection of susceptible people.