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目的:观察华法林联合毛花苷C在治疗老年扩张型心肌病临床应用价值。方法:选取本院100例老年扩张型心肌病患者进行实验分析,随机分为两组,应用组采用华法林联合毛花苷C的治疗方式,对照组单独采用华法林治疗,经过2个疗程的治疗后对比两组治疗前后的左室射血分数(LVEF)、舒张早晚期的最大血流速度比值(E/A)、左室舒张早期流速峰值(EPFV)、舒张晚期血流值(APFV)水平,然后检测相关的心脏功能:左室收缩末期容积(LVESV)、左室舒张末期容积(LVEDV)、左室内径(LV)、心胸比值(CTR),并且通过5 min步行对患者的心脏功能进行检测。结果:应用组总治疗有效率为86%;对照组总治疗有效率为68%,两组比较,差异具有统计学意义(P<0.05)。两组患者各项功能检测水平与治疗前都有改善,且应用组治疗效果比对照组更加明显,差异具有统计学意义(P<0.05)。同时5 min步行测验中应用组患者的康复水平优于对照组。结论:华法林联合毛花苷C治疗老年扩张型心肌病有较好的治疗效果。
Objective: To observe the clinical value of warfarin combined with curcumin C in the treatment of elderly patients with dilated cardiomyopathy. Methods: 100 elderly patients with dilated cardiomyopathy in our hospital were randomly divided into two groups. The treatment group was treated with warfarin combined with curcumin C. The control group was treated with warfarin alone. After two After treatment, the left ventricular ejection fraction (LVEF), the maximum blood flow velocity ratio (E / A), the peak left ventricular diastolic velocity (EPFV), the diastolic blood flow ( APFV), and then the related cardiac function was measured: left ventricular end-systolic volume (LVESV), left ventricular end diastolic volume (LVEDV), left ventricular diameter (LV) and cardiothoracic ratio (CTR) Cardiac function testing. Results: The total effective rate was 86% in the application group and 68% in the control group. There was significant difference between the two groups (P <0.05). The levels of various functional tests in both groups were improved before treatment, and the effect of treatment group was more obvious than the control group, the difference was statistically significant (P <0.05). At the same time, the rehabilitation level of the patients in the 5 min walk test was better than that of the control group. Conclusion: Warfarin combined with curcumin C treatment of elderly patients with dilated cardiomyopathy has a better therapeutic effect.