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目的 :探讨不同部位大脑半球脑梗死患者心电图与血浆肌酸激酶 同工酶 (CK MB)活性的变化。方法 :检测 15 6例首发急性大脑半球脑梗死患者的心电图和血浆CK MB活性 ,分析比较不同部位大脑半球梗死患者的心电图和血浆CK MB活性变化。结果 :右侧岛叶脑梗死患者快速心律失常和QTc延长发生率显著增加 ,左侧岛叶脑梗死患者ST段上升或下降显著增加 ,其他各种心电图改变各组间无明显区别。血浆CK MB活性升高亦主要见于岛叶梗死患者 ,血浆CK MB活性升高者心电图异常发生率明显增加 ,预后更差。结论 :造成心电图异常和血浆CK MB活性升高的大脑半球脑梗死部位主要是岛叶 ,对影响到岛叶的脑硬死患者应加强心肌保护和心脏监护。
Objective: To investigate the changes of electrocardiogram (ECG) and plasma creatine kinase (CK MB) activity in patients with cerebral hemispheric infarction at different sites. Methods: The electrocardiogram (ECG) and plasma CK MB activity in 15 6 patients with acute cerebral hemispheric infarction were measured. The changes of electrocardiogram and plasma CK MB activity in patients with different hemispheric infarcts were analyzed. Results: The incidences of tachyarrhythmia and QTc prolongation were significantly increased in patients with right isleesophageal infarction. The ST segment elevation and descent in patients with left islets were significantly increased. There was no significant difference between the other ECG changes in all groups. Plasma CK MB activity is also mainly seen in patients with insular island infarction, plasma CK MB activity increased ECG abnormalities increased significantly, the prognosis worse. CONCLUSION: Cerebral infarction caused by an abnormal electrocardiogram (ECG) and elevated plasma CK MB activity is predominantly insula, and myocardial protection and cardiac monitoring should be strengthened for those patients with insula that affect insula.