提出以锌试剂络合—分光光度法测定感冒通片中扑尔敏含量。本法利用锌试剂在酸性水溶液中与扑尔敏形成１∶１络合物，经氯仿提取后在５３３ｎｍ波长处测定，可消除其它成分及辅料的干扰。方法平均回收率为１００．８％（Ｓ＝１．５４，ｎ＝１２），本法灵敏度高，结果准确，适用于感冒通片的常规分析。 Proposed by zinc reagent complex - spectrophotometric determination of the content of chlorpheniramine tablets. This method uses zinc reagent to form a 1: 1 complex with chlorpheniramine in acidic aqueous solution, and after being extracted by chloroform, it is measured at the wavelength of 533 nm to eliminate the interference of other components and excipients. The average recovery rate of the method was 100.8% (S = 1.54, n = 12). This method has high sensitivity and accurate results and is suitable for the routine analysis of cold pass.