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我们应用改良的聚丙烯酰胺凝胶电泳方法检测了96例神经系统疾病(包括格林-巴利20例,多发性硬化7例,神经系统炎性疾患27例,神经系统非炎性疾病42例)脑脊液寡克隆区带。结果发现寡克隆区带阳性:格林-巴利组14例(70%).多发性硬化组4例(57.1%),神经系统炎性疾患组7例(25.9%),神经系统统非炎性疾患组3例(7.1%)。本研究表明脑脊液寡克隆区带检测对格林-巴利综合征和多发性硬化有一定的诊断价值。
We used a modified polyacrylamide gel electrophoresis method to detect 96 cases of neurological diseases (including 20 cases of Guillain-Barre, 7 cases of multiple sclerosis, 27 cases of nervous system inflammatory diseases, 42 cases of nervous system non-inflammatory diseases) Cerebrospinal fluid oligoclonal band. The results showed that oligoclonal band positive: Green-Barre group of 14 patients (70%). 4 cases (57.1%) in multiple sclerosis group, 7 cases (25.9%) in nervous system inflammatory disease group and 3 cases (7.1%) in non-inflammatory nervous system group. This study shows that detection of cerebrospinal fluid oligoclonal bands for diagnosis of Guillain-Barre syndrome and multiple sclerosis have some diagnostic value.