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目的探讨125I粒子组织间植入治疗晚期肺癌的近期疗效。方法 56例已确诊的晚期肺癌患者,通过TPS计算出所需植入粒子总数及每个CT层面上的粒子数及位置,在CT引导下行瘤体内粒子植入,植入后当时及术后5个月行CT扫描观察粒子分布情况、并发症的发生及临床疗效。结果 56例中,完全缓解(CR)17例,部分缓解(PR)28例,无变化(NC)8例,进展(PD)3例。局控率80.36%。结论 125I粒子组织间植入治疗晚期肺癌安全有效、创伤小、并发症少。
Objective To investigate the short-term effect of 125I seed implantation in the treatment of advanced lung cancer. Methods Fifty-six patients with advanced lung cancer who had been diagnosed with advanced lung cancer were enrolled in this study. TPS was used to calculate the total number of implanted particles and the number and location of particles on each CT plane. CT-guided implantation of tumor in vivo, Month CT scan observation of particle distribution, the occurrence of complications and clinical efficacy. Results Of the 56 cases, 17 were completely relieved (CR), 28 were partially relieved (PR), 8 were unchanged (NC) and 3 were PD. Bureau control rate of 80.36%. Conclusion The implantation of 125I seeds in the treatment of advanced lung cancer is safe and effective, with less trauma and fewer complications.