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本文综述氟有机化学的最新进展。论及:1.气溶胶直接氟化法,新的温和的氟化试剂——CH_3CO_2F,N-氟代二氢吡咯酮,R_F(?)(C_6H_5)CF_3SO_3(?)和喷雾干燥的KF。2.合成全氟烷基磺酸的新方法,如全氟烷基碘在金属活化下与SO_2在DMF中的反应,又如I(CF_2)_2O(CF_2)_2SO_2F与C_2F_4调聚和全氟卤代烷的亚磺化脱碘反应。3.惰性—CF_2—及—CF_3的新反应,如五氟一氯丙酮与KF的反应,多氯氟乙烷与硫酚钠的反应。4.具有生理活性的氟化物,如抗癌物fluorosesqisiloxane,杀虫剂29-fluorositosterol。
This article reviews recent advances in fluoroorganic chemistry. Discussion: 1. Aerosol direct fluorination method, new mild fluorinating reagent - CH_3CO_2F, N-fluorodihydropyrone, R_F (?) (C_6H_5) CF_3SO_3 (?) And spray-dried KF. 2. New methods for the synthesis of perfluoroalkylsulfonic acids, such as the reaction of perfluoroalkyl iodides with SO 2 in DMF under metal activation, and the reaction of I (CF 2) 2 O (CF 2) 2 SO 2 F with C 2 F 4 and perfluoroalkyl halides Sulfonated deiodination reaction. 3. Inert-CF2- and -CF3 new reactions, such as pentafluoroacetone and KF reaction, polychloroethane and thiophenolate reaction. 4. Physiologically active fluoride, such as anti-cancer substance fluorosesqisiloxane, insecticide 29-fluorositosterol.