论文部分内容阅读
目的探讨脐血输注疗法对慢性乙型重型肝炎的治疗效果。方法将60例慢性乙型重型肝炎随机分为脐血治疗组和对照组,均采用常规综合性治疗。但脐血治疗组加用静脉输注异体同血型脐血。比较两组患者治疗前后的多种临床疗效考核指标。结果①脐血治疗后患者血清总胆红素降低明显,胆碱脂酶、凝血酶原活动度明显改善,与对照组比较有显著性差异,P<0.05;②脐血治疗后患者红细胞、血红蛋白无明显下降,而对照组下降比较明显,两者比较有显著性差异,P<0.05;③脐血治疗后患者并发症下降,总有效率明显提高。结论脐血治疗可改善重型肝炎的肝功能,减少并发症,改善预后。可望成为慢性乙型重型肝炎患者重要的辅助治疗措施。
Objective To investigate the therapeutic effect of cord blood transfusion therapy on chronic severe hepatitis B Methods Sixty patients with chronic severe hepatitis B were randomly divided into cord blood treatment group and control group, all of them were treated by routine general treatment. However, umbilical cord blood treatment plus intravenous infusion of allogeneic cord blood. Comparison of two groups of patients before and after treatment of a variety of clinical evaluation indicators. Results ① Serum total bilirubin decreased significantly after treatment of umbilical cord blood, the activity of cholinesterase and prothrombin significantly improved compared with the control group (P <0.05); ② After treatment with cord blood, the levels of erythrocyte, hemoglobin No significant decline, while the control group decreased significantly, the two were significantly different, P <0.05; ③ umbilical cord blood patients after treatment decreased, the total effective rate was significantly increased. Conclusion Cord blood treatment can improve the liver function of severe hepatitis, reduce complications and improve prognosis. It is expected to be an important adjuvant therapy for patients with chronic severe hepatitis B.