本实验室以前的工作表明,动物在急性低氧条件下,中枢大量释放β-内啡肽,这是中枢对低氧的应激反应,而这种反应的结果引起低氧通气抑制。除了中枢反应外,是否还存在外周β-内啡肽系统对低氧的反应尚不清楚。为此,我们测定了在模拟3600m高度时人血浆中β-内啡肽含量的变化,并同时观察了这种变化与终末呼出气氧分压(P_(EO2))和氧饱和度(Sao_2)间的关系。 Previous work in our laboratory has shown that in acute hypoxia, animals release a large amount of β-endorphin in the central nervous system, which is the central stress response to hypoxia, and the result of this reaction is hypoxia-induced inhibition. In addition to the central response, the existence of the peripheral β-endorphin system response to hypoxia is unclear. To this end, we measured the changes of β-endorphin in human plasma at a simulated altitude of 3600m and observed the relationship between these changes and the end-expired partial pressure of oxygen (P_ (EO2)) and oxygen saturation (Sao_2 ) The relationship between.