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目的观察FC多糖的体内抑瘤作用。方法以荷S180、艾氏腹水癌实体瘤小鼠为模型,初步观察了来自传统中药的有效成分FC多糖的抑瘤作用。结果实验结果发现,小鼠在接种瘤细胞前连续灌胃给药10d,FC多糖能显著抑制小鼠移植性肿瘤的生长,平均抑瘤率均大于40%,同时FC多糖对荷瘤造成的脾和胸腺指数下降有一定的恢复作用。结论提示FC多糖将是一种有开发价值的抗肿瘤物质
Objective To observe the antitumor effect of FC polysaccharide in vivo. Methods The mice bearing S180 and Ehrlich ascites cancer solid tumors were used as a model to observe the anti-tumor effect of FC polysaccharide from traditional Chinese medicine. RESULTS: The experimental results showed that mice were continuously given intragastric administration for 10 days before inoculation of tumor cells. FC polysaccharide significantly inhibited the growth of transplanted tumors in mice, and the average tumor inhibition rate was greater than 40%. At the same time, FC polysaccharides caused spleen-induced spleen tumors. Decreased thymus index and a certain degree of recovery. Conclusions suggest that FC polysaccharides will be a valuable anti-tumor agent