患者男,39岁。因反复咳嗽、咳脓痰5年,加重伴哮喘1周于2006年4月12日入院。既往有慢性阻塞性肺疾病(COPD)合并肺气肿、肺大泡、支气管扩张病史,曾在我院多次住院。本次住院前1周咳嗽、咳痰症状明显加重,多为白色黏痰且不易咳出,并有哮喘发作,胸闷、烧灼感、烦躁不安,咽部及胸骨后有虫爬样感觉,自觉与往日发病症状不同。于入院当日晨7:00时胸闷、呼吸困难、窒息样哮喘发作,由120急救送入我院。入院体检:体温36.8℃,端坐呼吸,高度呼吸困难,两肺满布哮鸣音。实验室检查:WBC 6.0×10~9/L,中性0.730,淋巴0.178,酸性0.035。ESR 正常。胸部 X 线 Male patient, 39 years old. Due to repeated cough, cough purulent sputum for 5 years, aggravated with asthma for 1 week in April 12, 2006 admission. Past chronic obstructive pulmonary disease (COPD) with emphysema, bullae, bronchiectasis, hospitalized many times in our hospital. 1 week before the hospital cough, sputum symptoms were significantly worse, mostly white phlegm and difficult to cough, and asthma attack, chest tightness, burning sensation, irritability, throat and chest crawling insects after feeling, conscious and Symptoms of the past onset of different. On the morning of admission 7:00 am chest tightness, difficulty breathing, asphyxia-like asthma attack, 120 emergency first sent to our hospital. Admission medical examination: body temperature 36.8 ℃, sitting breathing, a high degree of difficulty breathing, lungs covered with wheeze. Laboratory tests: WBC 6.0 × 10 ~ 9 / L, neutral 0.730, lymph 0.178, acid 0.035. ESR is normal. Chest X-ray