巨细胞病毒(CMV)分别由Rowe、Smi-th、Weller 于1956年从动物和人体内分离出来,后经国际会议命名为巨细胞包涵体病和巨细胞单核细胞增多症。经过各国学者的广泛研究和临床观察,认为CMV 是人类最常见的寄生性病毒之一。可使新生儿致命致畸,长期潜伏于人体的CMV,伺机复燃,临床表现变化多端,主要有肺炎和肝炎,在免疫抑制的情况下,死亡率尤高。病理和发病机理 The cytomegalovirus (CMV) was isolated from animals and humans by Rowe, Smi-th, and Weller, respectively, in 1956 and was later named International Conferences for Cytomegalovirus Inclusion and Giant Cell Mononucleosis. After extensive research and clinical observation by scholars in various countries, CMV is considered as one of the most common parasitic viruses in humans. Can make the newborn fatal teratogenic, long-term latent in the human body CMV, opportunistic revival, the clinical manifestations of change, mainly pneumonia and hepatitis, in the case of immunosuppression, particularly high mortality. Pathology and pathogenesis