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流感病毒可以引起人类严重的呼吸系统疾病,甚至导致死亡。由于病毒具有高突变率及其抗原漂移、基因重配等特性,因此导致流感的反复暴发,甚至大流行。疫苗是预防流感最有效的手段,不同种类的流感疫苗在不同人群中会产生不同的免疫效果,本文就流感减毒活疫苗的临床效率作一综述。
Influenza virus can cause serious respiratory diseases in humans and even cause death. As the virus has a high mutation rate and antigenic drift, gene reassortment and other characteristics, resulting in recurrent and even flu pandemic. Vaccination is the most effective way to prevent influenza. Different kinds of influenza vaccines have different immune effects in different populations. This article reviews the clinical efficacy of live attenuated influenza vaccine.