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对３２例手术病理证实的肺癌和肺结核病人（其中鳞状上皮癌１６例，腺癌８例，小细胞肺癌４例，肺转移癌２例，肺结核２例），进行９９ｍＴｃ－ＴＦ ＳＰＥＣＴ显像和ＣＴ检查，将结果直接与手术结果对比，来评价肺和纵膈淋巴结病变。结果在肺癌原发灶，９９ｍＴｃ－ＴＦ ＳＰＥＣＴ显像具有较高的灵敏度（９３％， ２８／３０），但２例肺结核病灶也显示９９ｍＴｃ－ＴＦ的摄取增高。有５例手术证实伴有肿瘤中心坏死的肺癌病灶，其９９ｍＴｃ－ＴＦ ＳＰＥＣＴ显像示肿瘤中心部位放射性缺损。在纵膈淋巴结转移，９９ｍＴＣ－ＴＦ ＳＰＥＣＴ显像的特异性和灵敏度（８８， ８７％）优于ＣＴ扫描（５９％， ６７％）。可见９９ｍＴｃ－ＴＦ ＳＰＥＣＴ显像在评价肺癌原发灶和纵膈淋巴结转移中，特别是后者是一种准确和有效的方法。
Thirty-two patients with lung cancer and tuberculosis confirmed by pathology (including 16 cases of squamous cell carcinoma, 8 cases of adenocarcinoma, 4 cases of small cell lung cancer, 2 cases of metastatic lung cancer, and 2 cases of pulmonary tuberculosis) were performed with 99mTc-TF SPECT imaging and CT examinations were performed to compare the results directly with the results of the surgery to evaluate lung and mediastinal lymph node lesions. Results In primary lung cancer, 99mTc-TF SPECT imaging had higher sensitivity (93%, 28/30), but 2 cases of pulmonary tuberculosis also showed increased uptake of 99mTc-TF. There were 5 cases of lung cancer lesions with necrosis of the tumor centers confirmed by surgery. The 99mTc-TF SPECT imaging showed radioactive defects in the center of the tumor. In the mediastinal lymph node metastases, the specificity and sensitivity of the 99mTC-TF SPECT imaging (88, 87%) was superior to that of the CT scan (59%, 67%). It can be seen that 99mTc-TF SPECT imaging is an accurate and effective method for evaluating primary lung cancer and mediastinal lymph node metastasis, especially the latter.