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目的 探讨肺泡蛋白沉积症 (PAP)的X线、CT征象与临床病理的联系。方法 回顾性分析经病理确诊的 5例PAP的X线、CT征象及其临床症状、病理变化的特征。结果 5例X线片上均主要表现为弥漫分布结节状、斑片状阴影 ,CT上呈轮廓多样的边缘较清晰磨玻璃状、云雾状影 ,其中 3例间质内伴有纤维索条影。病理上 5例肺泡腔内充满红色无定形物质 ,3例有纤维组织增生。结论 PAP属一种复杂的肺部弥漫性疾病 ,其X线、CT征象具有一定特征性 ,对于显示病灶内部结构、确定病变性质CT优于X线 ,但最后确诊仍须结合临床病理
Objective To investigate the relationship between X-ray and CT findings of pulmonary alveolar proteinosis (PAP) and clinicopathology. Methods Retrospective analysis of 5 pathologically confirmed PAP X-ray, CT signs and clinical features, pathological changes. Results All the 5 cases showed diffusely distributed nodules and patchy shadows on the X-ray films. The edges of the CT images were clear and glassy and cloud-like. Among them, 3 cases had interstitial fibers . Five cases of pathological alveolar cavity filled with red amorphous material, three cases of fibrous tissue hyperplasia. Conclusions PAP is a complex pulmonary diffuse disease. The X-ray and CT findings have certain characteristics. For the purpose of displaying the internal structure of the lesion, PAP is superior to X-ray in determining the nature of the lesion, but the final diagnosis is still to be combined with clinical pathology