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血管内皮细胞损伤及功能紊乱在糖尿病血管并发症病变过程中扮演着重要角色,改善血管内皮功能成为治疗糖尿病血管并发症的研究方向。近年来的研究发现,中药单体在调节血管舒缩功能、恢复纤溶系统活性、调节生长因子及PKC的表达、抗炎等方面发挥了保护血管内皮细胞的作用,从而改善糖尿病血管病变,对防治糖尿病血管病变有积极作用。
Vascular endothelial cell injury and dysfunction plays an important role in the pathogenesis of diabetic vascular complications, and the improvement of vascular endothelial function has become the research direction for the treatment of diabetic vascular complications. In recent years, the study found that Chinese medicine monomer in the regulation of vasomotor function, restore fibrinolytic system activity, regulate the expression of growth factor and PKC, anti-inflammatory and other aspects of the role of protection of vascular endothelial cells, thereby improving diabetic vascular disease, Prevention and treatment of diabetic vascular disease have a positive effect.