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目的:探讨导致急性高原病的相关危险因素。方法:选择2010年4月—2012年10月赴玉树地区一线工作的救灾及建设人群共1 200例作为研究对象,研究分为两组,一组是患有急性高原病276名人员,二组为未患急性高原病者924名人员,年龄均在(20～50)岁,对他们进行回顾性调查,调查内容包括:急性高原病的症状评分表、一般情况、家庭遗传病史、家庭情况及艾森克问卷调查等方面。并对他们急进玉树地区(4 000m)后的12小时、24小时、3天、7天各测试1次SaO2、肺功能、ST段、心率、血压等指标,每次测试均选在相同时限内(如晨起体力活动前),于第六天、第七天晚连续行12小时呼吸睡眠检测;被检者必须处于安静状态。结果:急性高原病的发生与患者的BMI、吸烟、急性高原病家族史、不良情绪、肺功能、SaO2、ST段、心率、血压、呼吸睡眠检测等多个因素相关。结论:急性高原病是多种因素共同作用的结果。
Objective: To investigate the risk factors associated with acute altitude sickness. Methods: A total of 1 200 relief and construction workers working in the Yushu area from April 2010 to October 2012 were selected as research objects. The study was divided into two groups, one was 276 persons with acute altitude sickness and the other two groups 924 persons without acute altitude sickness were all aged 20 to 50 years. They were retrospectively surveyed. The contents of the survey included symptom score table of acute altitude sickness, general conditions, family history of hereditary diseases, family conditions, Eysenck questionnaire and so on. SaO2, pulmonary function, ST segment, heart rate and blood pressure were measured at 12, 24, 3 and 7 days after they reached the Yushu area (4 000 m) respectively. Each test was selected within the same time frame (Such as morning physical activity before), on the sixth day, seventh night continuous sleep breathing 12 hours; subjects must be quiet. Results: The incidence of acute altitude sickness was related to many factors such as BMI, smoking, family history of acute altitude sickness, bad mood, lung function, SaO2, ST segment, heart rate, blood pressure and respiratory sleep. Conclusion: Acute mountain sickness is the result of many factors.