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引言本世纪30年代中期,对氟(Fluori-de.F)作为一种重要杀虫、灭鼠剂使用,转而认识到氟是牙齿保健的主要成分。TrendleyDean(1931)最先对自来水中天然存在的氟浓度进行定量测定,并研究微量氟浓度的单位为ppm(1ppm=1mgF/L=0.056μmol/L=56.0μmol/L)。只要饮水中含有微量的氟就能减少儿童龋齿发病率的1/3或1/2,随后有人研究氟对妊娠期的影响。本文综述孕母及胎儿氟的代谢、毒性及应用氟的防治作用。
Introduction In the mid-1930s, the use of fluorine (Fluoro-de) as an important insecticide and rodenticide used to recognize that fluorine was the main component of dental care. TrendleyDean (1931) first quantified the naturally occurring fluorine concentration in tap water and investigated the trace fluoride concentration in ppm (1 ppm = 1 mg F / L = 0.056 μmol / L = 56.0 μmol / L). As long as the drinking water contains trace amounts of fluoride can reduce the incidence of dental caries in children 1/3 or 1/2, followed by the study of fluoride on the impact of pregnancy. This article reviews the metabolism and toxicity of Fetus and Fetus and the prevention and treatment of Fluorosis.