哮喘发作严重,持续24小时以上,经过治疗无效者称为哮喘持续状态。其发生与感染未能及时控制、过敏原未能去除、体液损耗过多(患者每日从呼吸道蒸发的水分可达2000毫升以上)、痰液浓缩形成多量粘液栓阻塞支气管以及体力过度消耗、精神过度紧张有关。患者张口呼吸,显著发绀,大汗淋漓,面色苍白,四肢厥冷,脉快,可呈现急性肺气肿体征,两肺可听到哮鸣音,继发感染可听到湿性罗音。但是由于粘液栓阻塞 Serious asthma attack, sustained more than 24 hours, after treatment ineffective known as asthma persistence. Its occurrence and infection failed to control in time, the allergen failed to remove, excessive body fluid loss (patients daily evaporation of water from the respiratory tract up to 2000 ml), sputum concentrated to form a large number of mucus plug block bronchial and physical over-consumption, the spirit Excessive tension related. Patients mouth breathing, significant cyanosis, sweating, pale, extremities Jueleng, pulse fast, showing signs of acute emphysema, wheezing can be heard in both lungs, secondary infection can be heard wet rales. But blocked by mucus plug