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目的观察侧脑室微创穿刺引流联合亚低温治疗脑室出血的临床疗效。方法将2009年6月-2012年5月入住合肥市第二人民医院治疗的脑室出血患者根据匹配条件分为两组:对照组行内科保守治疗;治疗组在内科保守治疗的同时行侧脑室微创穿刺引流联合亚低温治疗。比较两组治疗前后21 d神经功能缺损评分(CSS)和随访3个月时的日常生活能力(Barthel指数)。结果治疗组有效率高于对照组(72.3%VS 32.6%,P<0.05);两组治疗前后神经功能缺损评分差异有统计学意义(P<0.05);治疗3个月后Barthel指数治疗组为(81.6±7.2)分,大于内科对照组的(55.2±6.4)分,差异有统计学意义(P<0.05)。结论侧脑室微创穿刺引流联合亚低温治疗脑室出血较传统内科治疗有效,且有利于神经功能恢复。
Objective To observe the clinical effect of minimally invasive puncture and drainage of the lateral ventricle combined with mild hypothermia in the treatment of ventricular hemorrhage. Methods From June 2009 to May 2012, patients admitted to the Second People’s Hospital of Hefei City for treatment of intraventricular hemorrhage were divided into two groups according to the matching conditions: the control group received conservative treatment; the treatment group received lateral conservative treatment Create puncture and drainage combined with mild hypothermia. The neurological deficit scores (CSS) at 21 days before and after treatment and the daily living ability (Barthel index) at 3 months of follow-up were compared between the two groups. Results The effective rate of the treatment group was higher than that of the control group (72.3% VS 32.6%, P <0.05). There was significant difference in the score of neurological deficits between the two groups before and after treatment (P <0.05). After 3 months of treatment, Barthel index was (81.6 ± 7.2) points, which was significantly higher than that of the control group (55.2 ± 6.4) (P <0.05). Conclusion Minimally invasive puncture and drainage of the lateral ventricle combined with mild hypothermia in the treatment of ventricular hemorrhage is more effective than traditional medical treatment, and is conducive to nerve function recovery.