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目的:了解湖州市人感染H7N9禽流感病例的流行病学特征及外环境样本检测情况。方法:收集2013—2018年现住址为湖州市的人感染H7N9禽流感确诊病例的流行病学信息，同时采集暴露可疑环境样本进行病原学检测。运用Spearman相关分析法分析发病数与环境阳性检出率的关系。结果:2013—2018年湖州市确诊的人感染H7N9禽流感病例39例，死亡9例，病死率为23.08%。男性多于女性，病例主要60岁以上的老年群体和农民。病例溯源样本阳性检出率为8.47%（30/345），农贸市场活禽交易场所的阳性检出率为25.00%（127/508），发病数与样本、场所检出阳性率的Spearman相关系数分别为0.379和0.392。结论:中老年男性及农民是人感染H7N9禽流感的高发群体，活禽暴露是发病的高危因素。“,”Objective:To understand the epidemiological characteristics of human infection with avian influenza A (H7N9) virus in Huzhou City and monitoring results of H7N9 virus in external environment.Methods:The epidemiological information of confirmed cases with H7N9 virus infection living in Huzhou City from 2013 to 2018 was collected, and the samples exposed to the environment were collected for pathogenic detection. Spearman correlation analysis was used to analyze the relationship between the incidence of H7N9 virus infection and positive detection rate in the environment.Results:From 2013 to 2018, 39 cases with H7N9 virus infection were confirmed in Huzhou, and 9 cases died with the fatality rate of 23.08%. Male cases were more than female ones, and the majority was in the elderly population over 60 years old and farmers. The positive rates of household samples from the patients and samples from live poultry trading places in agricultural markets were 8.47% (30/345) and 25.00% (127/508) , respectively. Spearman correlation coefficient between the incidence of H7N9 virus infection and positive detection rates of household and market samples were 0.379 and 0.392, respectively.Conclusions:The elderly male population and farmers are susceptible groups for human infection with H7N9 virus. Exposure history of live poultry is the high risk factor of infection.