遗传毒性是指致突变物(化学、物理因素及生物因素)作用于有机体,使遗传物质在染色体水平、分子水平和碱基水平上受到各种损伤,从而造成的毒性作用。遗传毒性对人体的影响难以估量,不仅涉及接触者本身的健康,而且涉及到下一代,甚至下二代、三代子女的健康问题,有关工业(环境)化学物的遗传毒性一直以来倍受国内外职业卫生工作者关注。铅及其无机化合物广泛用于工业生产中,是一种古老的工业毒物和环境 Genotoxicity refers to the toxic effects caused by mutagens (chemical, physical and biological factors) acting on organisms that cause damage to genetic material at the chromosome level, molecular level and base level. The impact of genotoxicity on human beings is immeasurable not only in terms of the health of the contacts themselves but also in the health problems of the next and even second- and third-generation children. The genotoxicity of industrial (environmental) chemicals has long been at home and abroad Occupational health workers concerned. Lead and its inorganic compounds are widely used in industrial production, is an ancient industrial poison and environment