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目的分析小儿消化性溃疡的特征以及探讨其与幽门螺杆菌（ＨＰ）的关系。方法１４００例小儿行纤维胃镜检查并对胃粘膜通过组织培养、病理检查、快速尿素酶试验检测ＨＰ。结果行胃镜检查的小儿中消化性溃疡的检出率为１０５％（１４７／１４００），其中十二指肠溃疡（ＤＵ）占８７１％（１２８／１４７），胃溃疡（ＧＵ）占１１６％（１７／１４７），复合性溃疡占１４％（２／１４７）。年龄为（９５２±２９１）岁，男∶女为１９４∶１；＞６岁者占８３７％，以十二指肠溃疡多见，ＧＵ∶ＤＵ＝１∶２３２；≤６岁者的ＧＵ∶ＤＵ为１∶１。十二指肠溃疡发生于球部９５３％（１２２／１２８），单发溃疡占４４５％（５７／１２８），多发溃疡占１３３％（１７／１２８），霜斑样溃疡占４２２％（５４／１２８）。胃溃疡中单发７０６％（１２／１７），多发性溃疡２９４％（５／１７），多发生于胃窦部和胃角中段。胃溃疡中ＨＰ检出率为２３５％（４／１７），十二指肠溃疡中ＨＰ检出率为６４４％（５６／８７），溃疡复发者均伴ＨＰ感染。结论小儿消化性溃疡，好发于学龄期以上，以十二指肠溃疡为多见，十二指肠溃疡与ＨＰ感染密切相关，复发亦与其有关。
Objective To analyze the characteristics of children with peptic ulcer and explore its relationship with Helicobacter pylori (HP). Methods 1400 cases of children underwent fiber endoscopy and gastric mucosa through tissue culture, pathological examination, rapid urease test HP. Results The detection rate of peptic ulcer in children underwent gastroscopy was 105% (147/1400). Duodenal ulcer (DU) accounted for 871% (128/147), gastric ulcer (GU) Accounting for 11.6% (17/147), complex ulcer accounting for 14% (2/147). The age was (952 ± 291) years old, males and females were 194:1. The patients aged> 6 years accounted for 837%. Duodenal ulcer was more common. GU: DU was 1:23. 2; GU: DU ≤ 6 years old is 1: 1. Duodenal ulcer occurred in 953% (122/128) of the bulb, single ulcer accounted for 445% (57/128), multiple ulcer accounted for 133% (17/128), frostbite ulcer Accounting for 42 2% (54/128). Gastric ulcer in a single 70 6% (12/17), multiple ulcers 29 4% (5/17), occurred in the antrum and the middle of the stomach. The detection rate of HP in gastric ulcer was 235% (4/17). The detection rate of HP in duodenal ulcer was 644% (56/87). All the patients with recurrent ulcer had HP infection. Conclusions Pediatric peptic ulcer occurs predominantly in school age and is more common in duodenal ulcer. Duodenal ulcer is closely related to HP infection and relapse is also related to it.