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目的:探讨高原两个不同海拔地区藏、汉族阻塞性睡眠呼吸暂停综合征(OSAS)患者血压变异性的特点,初步明确高原缺氧对OSAS患者血压的影响,了解藏、汉族OSAS患者血压变异性是否存在差别。方法:应用多导睡眠图对研究对象进行睡眠呼吸监测,同期进行24h动态血压检查。结果:(1)同一海拔地区藏、汉族OSAS患者24h平均血压、收缩压变异系数、舒张压变异系数较同民族对照组均偏高,差异有统计学意义(P<0.05);(2)高海拔地区藏、汉族OSAS患者24h舒张压变异系数较低海拔藏、汉族OSAS患者高,差异有统计学意义(P<0.05)。结论:(1)高海拔地区藏、汉族OSAS患者的血压变异性变大,同海拔地区OSAS患者血压变异性无民族差异;(2)与低海拔地区藏、汉族OSAS患者相比,高海拔地区OSAS患者24h舒张压变异系数高。
Objective: To investigate the characteristics of blood pressure variability in Tibetan and Han patients with obstructive sleep apnea syndrome (OSAS) at two different altitudes in the plateau, and to determine the effects of hypoxia on the blood pressure in OSAS patients. To understand the changes of blood pressure variability Is there any difference? Methods: Polysomnography was used to monitor sleep apnea and 24-hour ambulatory blood pressure during the same period. Results: (1) The average blood pressure, systolic blood pressure coefficient of variation and coefficient of variation of diastolic blood pressure in Tibetan OSAS patients at the same altitude were significantly higher than those in the same ethnic group (P <0.05); (2) Altitude Tibet, Han OSAS patients 24h diastolic pressure coefficient of variation was lower in Tibet, Han OSAS patients, the difference was statistically significant (P <0.05). Conclusion: (1) The blood pressure variability of OSAS patients in Tibetan and Han nationality in high altitude area is larger than that of OSAS patients in high altitude area. (2) There is no ethnic difference in the variability of blood pressure among OSAS patients at high altitudes; (2) OSAS patients 24h diastolic blood pressure coefficient of variation.