本实验用半胱胺经口给药方法诱发大鼠十二指肠球部溃疡.在离体条件下,以肠电慢波的频率和振幅为指标,观察了溃疡时十二指肠各部位的电活动变化.结果表明:(1)溃疡病变均选择性地形成在十二指肠球部,溃疡中心在离幽门括约肌0.5cm左右处;(2)在幽门括约肌尾侧0.5cm处(形成渍疡部位)和1.0cm及2.0cm处(未形成溃疡部位)的溃疡大鼠十二指肠电慢波频率,均明显地高于对照组(P<0.5),而其振幅的变化不甚明显(P In this study, cysteamine was administered orally to induce duodenal ulcer in rats.Under the conditions of in vitro, the frequency and amplitude of slow wave of intestine were taken as indexes to observe the different parts of duodenum (1) ulcer lesions were selectively formed in the duodenal bulb, the ulcer center is about 0.5cm away from the pyloric sphincter; (2) 0.5cm at the caudal pyloric sphincter Ulcer site) and 1.0 cm and 2.0 cm (not formed ulcer site) of duodenal ulcer rats were significantly higher than the control group (P <0.5), and its amplitude did not change much Obviously (P