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目的探究高压氧治疗新生儿重度缺氧缺血性脑病、促进患儿康复的临床效果。方法将2015年1月—2017年5月在该院诊治的120例患有重度缺氧缺血性脑病的新生儿按照治疗方法的不同分为观察组与对照组,对照组给予常规药物治疗,观察组在常规药物治疗的基础上给予高压氧治疗,在1个疗程结束后患儿复查头部CT,在患儿出生1个月后进行新生儿行为神经(NBNA)测试、在患儿2岁时进行Bayley婴幼儿发育量表测试,综合评定治疗效果。结果 1个疗程结束后的头部CT复查观察组的正常率、患儿出生1个月、2岁后的两项测试评分、治疗的总有效率均高于对照组,差异有统计学意义(P<0.05)。结论高压氧对新生儿重度缺氧缺血性脑病有着较好的治疗效果,有利于患儿短期和长期的智能康复,值得临床推广与使用。
Objective To investigate the clinical effect of hyperbaric oxygen therapy on neonatal hypoxic-ischemic encephalopathy and promote the rehabilitation of children. Methods 120 newborns with severe hypoxic-ischemic encephalopathy diagnosed and treated in this hospital from January 2015 to May 2017 were divided into observation group and control group according to different treatment methods. The control group was given conventional drug treatment, The observation group was given hyperbaric oxygen therapy on the basis of conventional drug treatment. The head CT was reviewed in children after one course of treatment. The neonatal behavioral neuron (NBNA) test was performed one month after birth, When Bayley infant development scale test, a comprehensive evaluation of the treatment effect. Results After the end of one course of treatment, the head CT examination showed that the normal rate of the observation group was significantly higher than that of the control group (1 month after birth, 2 tests after 2 years, total effective rate) P <0.05). Conclusions Hyperbaric oxygen has a good therapeutic effect on neonatal hypoxic-ischemic encephalopathy, which is good for short-term and long-term intelligent rehabilitation in children and deserves clinical promotion and use.