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通腑汤由大黄、芒硝、枳实、厚朴、陈皮、半夏、木香、乌药、川楝子、炒莱菔子、当归、白芍组成 ,具有通里攻下、行气理气兼以养血活血之功效。对腹部手术后患者分别给予通腑汤肛肠灌注、口服 ,并设高渗盐水直肠灌注为对照。结果 :通腑汤肛肠灌注组在肠鸣音恢复时间 ,体表胃窦、升结肠和降结肠体表肌电平均振幅及平均过零频率升高 ,血浆胃动素升高 ,血浆降钙素基因相关肽降低方面均优于口服组及盐水组。提示 :直肠灌注通腑汤的治疗机制与影响胃肠激素的调控有关 ,还可能与药物对肠神经系统的调控和 /或肌源性调控的影响有关
Tongtong Tang consists of rhubarb, Glauber’s salt, Chinese Gorgon fruit, Magnolia officinalis, Citrus, Pinellia, woody, acacia, chuanxiongzi, fried radish, angelica, and white peony. Nourishing and activating blood. After abdominal surgery patients were given Tongyu Decoction perfusion, oral administration, and set up hypertonic saline rectal perfusion as a control. RESULTS: During the recovery of bowel sounds in the Tongluo anorectal perfusion group, the mean amplitude and mean zero frequency of surface antrum, ascending colon and descending colon were increased, plasma motilin was increased, and plasma calcitonin was increased. The reduction of gene-related peptides was superior to oral and saline groups. Tip: The therapeutic mechanism of rectal perfusion Tongqiao Decoction is related to the regulation of gastrointestinal hormones, and may also be related to the effect of drugs on the regulation of the enteric nervous system and/or the effect of myogenic regulation.