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目的:探讨单光子发射电子计算机断层扫描(SPECT)肾动态显像对原发性高血压(EH)早期肾损害的辅助诊断价值。方法:对EH41例行SPECT肾动态显像检查,测定肾功能参数,各段峰值、峰时、半排时间,以及肾小球滤过率(GFR)。同期检测患者血尿素、肌酐,尿NAG、尿β2-MG,比较各指标的诊断准确率。结果:肾动态显像GFR检测EH早期肾损害的阳性率为82.9%,显著高于尿β2-MG和NAG检测的阳性率(51.2%和63.4%,P<0.05)。结论:肾动态显像检查对明确EH早期肾损害诊断有较好的临床应用价值。
Objective: To investigate the diagnostic value of single photon emission computerized tomography (SPECT) renal dynamic imaging in the diagnosis of early renal damage of essential hypertension (EH). Methods: SPECT renal dynamic imaging examination was performed routinely on EH41. The renal function parameters, the peak value of each segment, the peak time, half of the time, and the glomerular filtration rate (GFR) were measured. Blood urea, creatinine, urinary NAG and urinary β2-MG were detected in the same period, and the diagnostic accuracy of each index was compared. Results: The positive rate of early renal damage in EH by GFR was 82.9%, which was significantly higher than that of urine β2-MG and NAG (51.2% vs 63.4%, P <0.05). Conclusion: Renal dynamic imaging examination has a good clinical value in the early diagnosis of EH.