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免疫机制引起的肾炎总的可分为两类:一是抗肾小球基膜抗体(antiGBM)引起的肾炎;二是肾外抗原的抗体在血中形成免疫复合物(immunocomplex,IC)沉积于肾小球引起的肾炎。此外最近又提出一种先在组织内沉着的抗原(或抗体)与血中抗体(或抗原)在局部进行反应形成IC,引起的肾病变。这是所谓免疫复合物局部形成机理(in situ IC formation)。本文仅就血中免疫复合物在肾小球内沉积的机理进行论述。由于抗原抗体的性状不同,补体系统及其所派生的
Nephritis caused by the immune mechanism can be divided into two categories: one is anti-glomerular basement membrane antibody (antiGBM) -induced nephritis; two is the anti-renal antigens antibodies in the blood to form immune complexes (immunocomplex, IC) deposition Glomerular nephritis. In addition, recently, an antigen (or antibody) that is semitranslucent in a tissue is locally reacted with an antibody (or antigen) in the blood to form an IC-induced nephropathy. This is called in situ IC formation. This article discusses only the mechanism of immune complexes in the glomerular deposition of blood. Due to the different antigen-antibody traits, the complement system and its derived