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1987年以来,作者采用Haemonetic-V50型血细胞分离机对27例病人(男11例,女15例,另1例为6岁儿童,年龄20～57岁)进行了115次血浆交换疗法(PE)。结果:20例有效,其中15例显效(急性眠尔通中毒、Evans综合征溶血危象、原发性巨球蛋白血症、系统性硬化症并多发性骨髓瘤各1例,格林-巴利综合征2例,全身性红斑性狼疮3例,重症肌无力危象6例)。出现并发症30次,占26.1％,本组无1例直接因PE造成死亡。由此认为:对用传统方法治疗无效的病例,以及尚无适当治疗方法的疾病,特别是某些危重病人,PE可能获得效果。PE前尽可能治疗感染病灶,有助于感染的防治和提高PE的疗效。
Since 1987, the authors performed 115 plasma exchange therapy (PE) sessions on 27 patients (11 males and 15 females, and a 6-year-old child aged 20-57 years) in a Haemonetic-V50 hemocytometer. . Results: Twenty cases were effective, of which 15 cases were markedly effective (acute sleep poisoning, Evans syndrome hemolysis crisis, primary macroglobulinemia, systemic sclerosis and multiple myeloma in 1 case, 2 cases of syndrome, 3 cases of systemic lupus erythematosus, 6 cases of myasthenia gravis crisis). Complications occurred 30 times, accounting for 26.1%, no one in this group directly due to death caused by PE. From this point of view, PE is likely to have an effect on those patients who are ineffective with traditional methods and those that do not have appropriate treatment, especially in some critically ill patients. As much as possible before the treatment of infected lesions of PE, contribute to the prevention and treatment of infection and improve the efficacy of PE.