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目的针对白血病患者化学治疗(化疗)后口腔溃疡及疼痛问题,探讨其治疗及护理措施。方法 2010年10月-2012年2月,将98例白血病化疗后发生口腔溃疡患者分为观察组、对照组各49例,观察组使用重组人白细胞介素11(rhIL-11)配置为漱口液治疗,对照组使用重组人粒细胞刺激因子注射液(GM-CSF)配置为漱口液治疗。结果治疗3 d后,观察组患者口腔黏膜反应分度情况明显好于对照组,观察组患者口腔溃疡愈合时间较对照组好。结论使用rhIL-11可有效治疗白血病患者化疗后口腔溃疡的发展与愈合,有利于化疗计划的顺利完成。
Objective To investigate the treatment of oral ulcer and pain in patients with leukemia after chemotherapy (chemotherapy) and to discuss its treatment and nursing measures. Methods From October 2010 to February 2012, 98 patients with oral ulcer after chemotherapy for leukemia were divided into observation group and control group with 49 cases each. The observation group was given rhG-11 as mouthwash The control group was treated with recombinant human granulocyte-stimulating factor (GM-CSF) for mouthwash. Results After 3 days of treatment, the oral mucosal response index in the observation group was significantly better than that in the control group. The healing time of oral ulcer in the observation group was better than that of the control group. Conclusion The use of rhIL-11 can effectively treat the development and healing of oral ulcer after chemotherapy in patients with leukemia, which is beneficial to the successful completion of chemotherapy.