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目的了解本溪市中心城区的2型糖尿病患者高尿酸血症(HUA)患病情况及其相关因素。方法对常住本溪市中心城区的2276例2型糖尿病患者进行问卷调查,检测血尿酸,采集临床资料,应用SPSS13.0软件进行统计分析。结果 2型糖尿病患者HUA患病率为16.21%。女性患者随年龄的增长HUA患病率呈上升趋势(x~2=18.01,P<0.05),绝经期后妇女HUA患病率为18.60%,高于绝经期前妇女(10.16%),差别有统计学意义(x~2=9.583,P<0.05)。高嘌呤饮食、饮酒、有糖尿病家族史、体质指数(BMI)≥24 kg/m~2、高血压、血脂异常、伴有冠心病、卒中、糖尿病肾病和糖尿病视网膜病变的2型糖尿病患者HUA患病率高于非上述状况者(P<0.05)。HbA_(1C)与HUA呈负相关(r=-0.385,P<0.01)。结论高嘌呤饮食、饮酒、有糖尿病家族史、BMI≥24 kg/m~2、高血压、血脂异常、伴有并发症是2型糖尿病合并HUA的危险因素。
Objective To understand the prevalence of hyperuricemia (HUA) and its related factors in type 2 diabetic patients in downtown Benxi. Methods A total of 2276 patients with type 2 diabetes mellitus who lived in central Benxi City were investigated by questionnaire, serum uric acid was measured and clinical data were collected. SPSS13.0 software was used for statistical analysis. Results The prevalence of HUA in type 2 diabetic patients was 16.21%. The prevalence of HUA in female patients increased with age (x ~ 2 = 18.01, P <0.05). The prevalence of HUA in postmenopausal women was 18.60%, which was higher than that in premenopausal women (10.16%), the difference was Statistical significance (x ~ 2 = 9.583, P <0.05). High purine diet, alcohol consumption, family history of diabetes, body mass index (BMI) ≥ 24 kg / m 2, hypertension, dyslipidemia, type 2 diabetes with coronary heart disease, stroke, diabetic nephropathy and diabetic retinopathy HUA The prevalence rate was higher than those who did not (P <0.05). HbA_ (1C) was negatively correlated with HUA (r = -0.385, P <0.01). Conclusion High purine diet, alcohol consumption, family history of diabetes, BMI≥24 kg / m ~ 2, hypertension, dyslipidemia and complication are the risk factors of type 2 diabetes with HUA.