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我院于1978年10月至1979年3月,对部分新生儿肌内注射维生素D_3以预防佝偻病。现小结如下。一、观察方法 1.新生儿生后3～7天,给予维生素D_330万单位,一次肌注,共68人(预防组)。 2.同期,以不注射维生素D_3的42个新生儿作为对照。 3.两组均于42天、3月、4月、5月、6月随访检查一次。 4.随访检查项目:1)临床症状及体征——多汗、夜惊、乒乓头。2)3月和6月时各测定一次血碱性磷酸酶(AKP),改良金氏法(微量),以≥30单位为增高;同时进行腕部X线摄片。 5.按1977年黑龙江全国佝偻病防治科研协作组会议修订的诊断标准进行诊断。
Our hospital from October 1978 to March 1979, part of the neonatal intramuscular injection of vitamin D_3 to prevent rickets. Now summarized as follows. First, the observation method 1. Neonatal 3 to 7 days after giving vitamin D_330 million units, a muscle injection, a total of 68 (prevention group). In the same period, 42 newborns without vitamin D_3 were taken as control. 3. The two groups were followed up in 42 days, March, April, May and June. 4. Follow-up inspection items: 1) clinical symptoms and signs - sweating, night scared, ping-pong head. 2) In March and June, each determination of blood alkaline phosphatase (AKP), modified King’s method (trace), with ≥ 30 units for the increase; at the same time for wrist X-ray. 5. According to the 1977 National Rickale Disease Prevention and Treatment of Heilongjiang research collaboration group revised diagnostic criteria for diagnosis.