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用动态心电图监测国产普罗帕酮静注治疗老年前期及老年期快速型心律失常40例共42例次,并对其中5例用高效液相色谱法测定其血药浓度。42例次中显效20例次(47.6%)有效8例次(19.0%),总有效率66.7%。建议进一步进行血药浓度监测的研究,以实现普罗帕酮治疗的个体化方案。
A total of 42 cases of 40 cases of intravenous propafenone were monitored by dynamic electrocardiogram (ECG) in elderly patients with premature senility and senile tachyarrhythmia. Five of them were tested for plasma concentration by high performance liquid chromatography. Of 42 cases, 20 cases were effective (47.6%) and 8 cases (19.0%) effective, with a total effective rate of 66.7%. It is recommended that further studies of plasma concentration monitoring be conducted to achieve individualized regimens of propafenone.