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有充分的证据表明,目前随机对照试验(RCT)的报告质量不尽如人意。最近的方法学调查表明,不恰当的报告及试验设计将使治疗措施的效果产生偏倚。这种系统偏差正严重损害RCT本可摒弃系统偏差的特征。RCT中的系统偏差反映出了科学性差,而科学性差会严重影响正确的伦理标准。科学家
There is good evidence that the current RCT reporting is less than satisfactory. Recent methodological surveys have shown that inappropriate reporting and trial design will bias the efficacy of treatment measures. This systematic bias is seriously compromising the RCT’s ability to eliminate systematic bias. The systematic bias in RCTs reflects poor science, while bad science severely affects the correct ethical standards. the scientist