agonist相关论文
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Background and purpose:Drug resistance in epilepsy is considered as a complicated and multifactorial problem.Insufficien......
Objective To identify the agonists for Neuromedin U 2 receptor by using NMU2R cell line which was established by cotrans......
Objective It has been shown that sigma-1 receptor modulated many biological function and play an important role in neuro......
Hypoxia-inducible factor-2(HIF-2)is a heterodimeric transcription factor formed through the dimerization of an oxygensen......
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Regulative effect of endogenous cannabinoid receptor type 1 agonist (m)VD-hemopressin(α) on sleep-wa
The cannabinoids were reported to play important roles in the modulating of physiological functions, including sleep-wak......
Effects of β 3-adrenoceptor activation on lipids, glucose metabolism and atherosclerosis plaque in a
Objective: To study the effects of β 3-adrenoceptor (β3-AR) activation on lipid, glucose metabolism and atheroscleroti......
Eltrombopag-related renal vein thromboembolism in a patient with immune thrombocytopenia: A case rep
BACKGROUND Eltrombopag is an orally administered thrombopoietin receptor agonist linked to a heightened risk of treatmen......
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Establishment of HEK293 Cell Lines Stably Expressing NPS Receptor and The Screening of High Efficien
Neuropeptide S receptor display widespread locatization in the central nervous system[1],and the NPS/NPSR system,pot......
Discovery of Novel Agonist of Transport inhibitor response 1 through Structure-Based Virtual Screeni
It is well known that Auxin plays a key role in controlling many aspects of plant growth and development.Indole-3-ac......
Objective:To investigate the pharmacological potential of Argemone mexicana in treating constipation and emesis by using......
Different Pretreatments before Application of GnRH Antagonist Protocol in Controlled Ovarian Hyperst
Objective To analyze the clinical features and outcome of patients who used different pretreatments before application o......
Obstructive airway disease is a complex disease entity including several maladies characterized by bronchoconstriction a......
下丘脑之促性腺素释放激素(LHRH),通过控制黄体生成素(LH)和囊泡刺激素(FSH)影响着生殖系统的功能。LHRH人工合成剂(agonist)及其......
The influence of β_2AR polymorphisms as a predictor of successful short acting β_2-agonist nebulizat
Aim:In this study,we would like to determine associations between β2-Adrenergic Receptor(β2AR)polymorphisms at codon 1......
PPARγ agonist pioglitazone reverses memory impairment and biochemical changes in a mouse model of ty
OBJECTIVE Pioglitazone,known as a peroxisome proliferator-activated receptor γ(PPARγ) agonist,is used to treat type 2 ......
Revised Super-long Down-regulation Protocol Improves the Outcome of Infertile Patients with Repeated
Objective To investigate the outcome of revised super-long down-regulation protocol(RSDP) for in vitro fertilization / i......
Ohmefentanyl has significant inhibitory actions on the electrically evoked contractions of guinea pigileum and mouse va......
Effect of glucagon-like peptide-1 agonist on insulin signaling pathway in skeletal muscle of mice wi
Objective To study the effect of glucagon-like peptide-1 agonist(exendin-4)on insulin signaling pathway in skeletal musc......
Risk of pancreatic adverse events associated with the use of glucagon-like peptide-1 receptor agonis
AIM: To systematically assess risk of pancreatic adverse events with glucagon-like peptide-1(GLP-1) receptor agonist and......
Protective effect of glucagon-like peptide-1analogue on cardiomyocytes injury induced by hypoxia/reo
Objective To investigate the effect of glucagon-like peptide-1(GLP-1)receptor agonist liraglutide on hypoxia/reoxygenati......
A novel PPAR alpha/gamma dual agonist inhibits cell growth and induces apoptosis in human glioblasto
AIM: To examine the effect of a novel peroxisome proliferator-activated receptor (PPAR) α/γ dual agonist TZD18 on cell......
Comparison between a GnRH Agonist and a GnRH Antagonist Protocol for the Same Patient Undergoing IVF
In order to compare GnRH agonist with antagonist protocol for the same patient during controlled ovarian stimulation cyc......
目的 观察鞘内注射大麻素受体2(CB2)激动剂JWH015对骨癌痛小鼠痛行为的影响.方法 雄性C3H/HeN小鼠32只随机分为4组(n=8):空白组(C)......
Determination of structure-activity relationships between fentanyl analogs and human μ-opioid recept
Fentanyl is a potent and widely used clinical narcotic analgesic, as well as a highly selective μ-opioid agonist. The p......
Objective To evaluate the efficacy and safety of a new long-acting β2 agonist hydrochloric bambuterol for treating asth......
To investigate whether the polymorphisms of β2-adrenergic receptor (β2-AR) at position 16, 27, 164 are asso-ciated wit......
目的 :研究汉族国人中 β2 肾上腺素受体( β2 AR )遗传多态性与夜间哮喘的相关性。方法 :应用聚合酶链反应———等位基因特异性......
The effect and mecbanism of kappa opiate receptor agonist and high-frequency electrostimulation of acupoints in treating......
AIM: To study the relationship between some serotonergicsubreceptors and sleep stages and the effects of immune promote......
Hyposmotic membrane stretch potentiated muscarinic receptor agonist-induced depolarization of membra
AIM:To investigate the relationship betweenhyposmotic membrane stretch and muscarinic receptoragonist-induced depolariz......
AIM: Irritable bowel syndrome (IBS) is a functional bowel disorder. Its major symptom is bowel dysmotility, yet the mech......
AIM: To determine the effects of prophylactic peroxi-some proliferator-activated receptor (PPARγ) agonist administratio......
Constitutive androstane receptor agonist, TCPOBOP,attenuates steatohepatitis in the methionine choli
AIM:To ascertain whether constitutive androstane receptor(CAR)activation by 1,4-bis-2-(3,5,-dichloropyridyloxy)benzene(T......
2008548 The effects of pioglitazone on the process of oxidative stress in acute pancreatitis induced by cerulein.WAN Hon......
Liver X receptor agonist T0901317 reduces atherosclerotic lesions in apoE~(-/-) mice by up-regulatin
In this study, we studied the effect of liver X receptor (LXR) agonist T0901317 on Niemann-Pick C1 protein (NPC1) expres......
Serotonin receptor agonist quipazine promotes proliferation and apoptosis of human hepatocyte strain
BACKGROUND:Liver disease is commonly seen in the clinic and its pathological characteristic is combined hepatocellular d......
EP4 agonist alleviates indomethacin-induced gastric lesions and promotes chronic gastric ulcer heali
AIM: To investigate EP4-selective agonist effect on indomethacin-induced gastric lesions and on the spontaneous healing ......
A-α-CAO induces weak analgesia with very short duration in mice and is able to antagonize the analgesic effect of morph......
THE ANTAGONISTIC EFFECTS OF TETRAHYDRO-PROTOBERBERINES ON DOPAMINE RECEPTORS: ELECTROPHYSIOLOGICAL S
Tetrahydroprotoberberines (THPBs), including (-)-stepholidine ((-)-SPD), (-)-tetrahydropalmatine ((-)-THP) and tetrahydr......
AIM:To investigate the effect of GW4064 on the expression of adipokines and their receptors during differentiation of 3T......
Peroxisome proliferator-activated receptor-delta agonist ameliorated inflammasome activation in nona
AIM: To evaluate the inflammasome activation and the effect of peroxisome proliferator-activated receptors(PPAR)-δ agon......
Effect of adenosine A2A receptor agonist combined with bone marrow mesenchymal stem cells transplant
Objective To investigate the therapeutic effect and possible mechanism of adenosine A2A receptor agonist(CGS21680)combin......
Hormonal Regulation of Expression of Tissue Type Plasminogen Activator and Plasminogen Activator Inh
In the present study, gonadotropin and gonadotropin-releasing hormone (GnRH) regulation of tPA and PAI-1 expression in P......
