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目的:观察该院足月儿呼吸窘迫综合征(NRDS)的发病特点,并使用多因素分析筛选影响NRDS发病的相关临床因素。方法:分析该院2006年1月～2011年1月5年间足月儿NRDS临床资料58例,另取同期未合并NRDS的足月新生儿84例作为对照组,对照两组的性别、胎龄、胎次、体重、剖宫产率、宫内窘迫、分娩窒息、有无脐带绕颈、母亲糖尿病、妊娠高血压等相关临床资料,使用Logistic逐步回归法筛选相关变量。结果:两组在胎龄、胎次、有无脐带绕颈、妊娠高血压等方面没有统计学差异(P>0.05),在性别、体重、剖宫产率、宫内窘迫、分娩窒息、母亲糖尿病等相关临床资料方面存在统计学差异(P<0.05),Logistic回归分析显示患儿的体重、剖宫产率、宫内窘迫、分娩窒息、母亲糖尿病进入回归模型与RDS的发生密切相关(P<0.05)。结论:低体重、剖宫产、分娩时窒息、母亲糖尿病是足月儿RDS发生的高危因素。
Objective: To observe the incidence of neonatal respiratory distress syndrome (NRDS) in this hospital and use multivariate analysis to screen the relevant clinical factors that affect the incidence of NRDS. Methods: 58 cases of term neonates with NRDS were enrolled in this study from January 2006 to January 2011. Another 84 full-term newborns without NRDS during the same period were selected as control group. , Parity, birth weight, cesarean section rate, intrauterine distress, birth asphyxia, with or without umbilical cord around the neck, maternal diabetes, pregnancy-induced hypertension and other related clinical data, using Logistic regression to screen the relevant variables. Results: There was no significant difference between the two groups in terms of gestational age, parity, presence or absence of umbilical cord around the neck, and gestational hypertension (P> 0.05). There were no significant differences in gender, weight, cesarean section rate, Diabetes and other related clinical data (P <0.05). Logistic regression analysis showed that weight, cesarean section rate, intrauterine distress, childbirth asphyxia and maternal diabetes were closely related to RDS <0.05). Conclusion: Low birth weight, cesarean section, asphyxia during delivery and maternal diabetes are the risk factors of full-term RDS.