论文部分内容阅读
马兜铃酸用于癌的化疗、放疗时,有维持白细胞数的功能。国内曾将其扩大应用于抗感染、肺心病等。但我们发现马兜铃酸明显地促进动物移植肿瘤的生长。为了确保患者用药安全,我们对马兜铃酸的促癌作用及其机制作了进一步的研究。
Aristolochic acid has the function of maintaining white blood cell count when used for cancer chemotherapy or radiotherapy. Domestically, it has been applied to anti-infection and pulmonary heart disease. However, we found that aristolochic acid significantly promoted the growth of transplanted tumors in animals. In order to ensure the safety of the patient’s medication, we further studied the carcinogenic effects of aristolochic acid and its mechanisms.