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目的分析肛管癌单纯放疗的治疗结果和预后情况。材料与方法法国蒙贝利埃医学院附属肿瘤医院从１９８７年到１９９２年，用单纯放射治疗３７例肛管癌患者，随访大于６０月。结果局部控制率２年为５８．０％，５年为３０．５％，平均生存时间为８７月，平均无病生存时间为３３月。治疗失败为淋巴结转移２４％，联合局部复发１３．５％，严重并发症５％。并发症及后遗症中，局部疼痛多见占３５．１％，其次为直肠间断性出血１８．９％，肛管坏死２．７％，肛管纤维化伴狭窄２．７％。结论根据临床统计分析预后因素与临床分期、组织学类型、分化程度、年龄等因素有关。
Objective To analyze the treatment outcome and prognosis of radiotherapy for anal canal cancer. MATERIALS AND METHODS From 1987 to 1992, 37 patients with anal canal cancer were treated with radiotherapy alone. The follow-up time was greater than 60 months. Results The local control rate was 58.0% at 2 years, 30.5% at 5 years, and the average survival time was 87 months. The average disease-free survival time was 33 months. Treatment failure was associated with lymph node metastasis of 24%, combined local recurrence of 13.5%, and severe complications of 5%. In complications and sequelae, local pain accounted for 35.1%, followed by intermittent rectal bleeding 18.9%, anal canal necrosis 2.7%, anal fibrosis with stenosis 2.7%. Conclusion According to clinical statistics, prognostic factors are related to clinical stage, histological type, differentiation degree, age and other factors.