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目的:对成都市2004～2006年出生缺陷监测结果进行分析,并与同期国家级出生缺陷监测单位监测结果进行比较,为制定有效的干预措施提供依据。方法:按照中国出生缺陷监测中心2006年制定的出生缺陷监测方案的要求,对成都市及10家国家级出生缺陷监测单位2004～2006年收集的围产儿出生缺陷资料进行分析,对成都市住院分娩满28周至出生后7天的围产儿进行登记、检查。结果:成都市2004～2006年出生缺陷发生率分别为8.33‰、10.31‰、11.80‰,呈逐年上升趋势,同期国家级监测单位出生缺陷发生率明显高于成都市;成都市2004～2006年出生缺陷发生顺位依次为外耳畸形、多指(趾)、总唇裂、并指(趾)、先天性心脏病。结论:提高围产保健技术,普及产前筛查,提高产前诊断水平,是降低出生缺陷发生率,提高出生人口素质的重要手段。
OBJECTIVE: To analyze the monitoring results of birth defects in Chengdu from 2004 to 2006 and compare them with the monitoring results of national birth defects monitoring units in the same period, so as to provide basis for making effective intervention measures. Methods: According to the birth defects monitoring program established by China Center for Birth Defects Monitoring in 2006, the data of birth defects collected in Chengdu and 10 national birth defects monitoring units from 2004 to 2006 were analyzed. The data of hospital delivery in Chengdu Perinatal children who have completed 28 weeks to 7 days after birth are registered and examined. Results: The incidence of birth defects in Chengdu from 2004 to 2006 were 8.33 ‰, 10.31 ‰ and 11.80 ‰, respectively, showing an upward trend year by year. The incidence of birth defects in state-level monitoring units was significantly higher than that in Chengdu during the same period. Chengdu was born between 2004 and 2006 The order of defects was external ear deformity, multiple fingers (toes), total cleft lip, and fingers (toes) and congenital heart disease. Conclusion: Improving perinatal care technology, popularizing prenatal screening and improving prenatal diagnosis are important means to reduce the incidence of birth defects and improve the quality of birth population.