论文部分内容阅读
Novel C-17-chloro-substituted derivative of vinorelbine or vinflunine has been regio-selectively synthesized via the chlorination reaction in the presence of Lewis acid.The catalyst Cp2TiCl2 plays a key role in the chlorination reaction.
Novel C-17-chloro-substituted derivative of vinorelbine or vinflunine has been regio-isolated synthase via the chlorination reaction in the presence of Lewis acid. Catalyst Cp2TiCl2 plays a key role in the chlorination reaction.